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Peptide record

TPDB18666

Antibacterial Antifungal standard
52 amino acids
Basic Information
3D PDB MODEL
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TPDB18666
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 52-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
DTFDYKKFGYRYDSLELEGRSISRIDELIQQRQEKDRTFAGFLLKGFGTSAS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C272H418N74O85
NCHMPWV
RDGLFS
6084.76
7.13
9
9
18
+0
2.82
-0.808
63.85
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
4470
0.73
14
Residue Composition
number
2
A
5
R
0
N
5
D
0
C
4
E
3
Q
5
G
0
H
3
I
5
L
4
K
0
M
5
F
0
P
5
S
3
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 2 R: 5 N: 0 D: 5 C: 0 E: 4 Q: 3 G: 5 H: 0 I: 3 L: 5 K: 4 M: 0 F: 5 P: 0 S: 5 T: 3 W: 0 Y: 3 V: 0
Chemical Descriptors
52 reviewed residue count
C272H418N74O85 sequence-only estimate (linear, free termini)
6084.76 sequence-only estimate (linear, free termini)
7.13 sequence-only estimate (linear, free termini)
+0 sequence-only estimate (linear, free termini)
2.82 sequence-only estimate (linear, free termini)
-0.808 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against B. subtilis and E. carotorora.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against B. subtilis and E. carotorora.