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Peptide record

TPDB18662

Antibacterial Toxicity modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
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TPDB18662
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 11-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
DSTXAGXXXXX
Physicochemical Analysis
C16H27N5O10
RNCEQHILKMFPWYV
ADGST
449.42
3.10
0
1
1
-1
1.34
-0.327
9.09
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C16H27N5O10
449.42
3.10
-1
1.34
-0.327
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Assembly and clustering of natural antibiotics guides target identification. | Nat Chem Biol | 2016
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Assembly and clustering of natural antibiotics guides target identification. | Nat Chem Biol | 2016
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Chinese hamster ovary cells CHO-K1

Target

Chinese hamster ovary cells CHO-K1

Source & Reference

NA
DBAASP
Biosynthetic Studies of Telomycin Reveal New Lipopeptides with Enhanced Activity. | J Am Chem Soc | 2015