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Peptide record

TPDB18627

Antibacterial Antiviral Toxicity standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB18627
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 15-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
DSGEGDFLAEGGGVR
Physicochemical Analysis
C60H92N18O25
NCQHIKMPTWY
G
1465.50
3.59
1
4
4
-3
5.70
-0.580
52.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
2
D
0
C
2
E
0
Q
5
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 2 C: 0 E: 2 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
15
C60H92N18O25
1465.50
3.59
-3
5.70
-0.580
Evidence Records 4 records
Evidence 1 Activity

Activity

<10% Cell death
Toxicity
100 µg/mL
Cytotoxic
<10% Cell death | 100 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Antiviral Activity of Synthetic Peptides Derived from Physiological Proteins. | Intervirology | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
A Peptide Found in Human Serum, Derived from the C-Terminus of Albumin, Shows Antifungal Activity In Vitro and In Vivo. | Microorganisms | 2020
Evidence 3 Activity

Activity

0.38% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0.38% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Peptide Found in Human Serum, Derived from the C-Terminus of Albumin, Shows Antifungal Activity In Vitro and In Vivo. | Microorganisms | 2020
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.30654366]<10% cytotoxicity against Vero cells at the concentration of 100µg/ mL.

Source & Reference

NA
DRAMP
Intervirology. 2018 61(4):166-173.