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Peptide record

TPDB18617

Antibacterial Antifungal standard
119 amino acids
Basic Information
3D PDB MODEL
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TPDB18617
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 119-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
DRGYGGGRRGGGYGGGGYGGGGYGGGGGGYGGGVGGGRGGGGGLGGGRGGGGGVIDGKDDVGLGGGGYGGGLGGGQGGGGGLGGGQGGGGGLGGGRGGGGYGGGGGGYGGGKYGGGKYG
Physicochemical Analysis
C391H584N142O140
ANCEHMFPSTW
G
9513.80
9.86
9
4
19
+5
2.46
-0.593
26.97
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
14900
156.61
12
Residue Composition
number
0
A
6
R
0
N
4
D
0
C
0
E
2
Q
85
G
0
H
1
I
5
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
10
Y
3
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 4 C: 0 E: 0 Q: 2 G: 85 H: 0 I: 1 L: 5 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 10 V: 3
Chemical Descriptors
119
C391H584N142O140
9513.80
9.86
+5
2.46
-0.593
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2-5 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active primarily against E. coli (MIC 2-5 uM) evaluated using a mixture of peptides. This is a bacteriostatic effect. The growth of S.
Evidence 2 Activity

Activity

MIC
Antibacterial
>10 µM

Target

Staphylococcus aureus was inhibited

Source & Reference

NA

Other

uM) evaluated using a mixture of peptides. This is a bacteriostatic effect. The growth of S. aureus was inhibited (MIC >10 uM) and no inhibition was observed against C-albicans up to 5 uM.
Evidence 3 Activity

Activity

MIC
Antifungal
2-5 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

Active primarily against E. coli (MIC 2-5 uM) evaluated using a mixture of peptides. This is a bacteriostatic effect. The growth of S.
Evidence 4 Activity

Activity

MIC
Antifungal
>10 µM

Target

Staphylococcus aureus was inhibited

Source & Reference

Antifungipept

Other

uM) evaluated using a mixture of peptides. This is a bacteriostatic effect. The growth of S. aureus was inhibited (MIC >10 uM) and no inhibition was observed against C-albicans up to 5 uM.