Back to search

Peptide record

TPDB18614

Antibacterial Antifungal standard
120 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB18614
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 120-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
DRGYGGGRRGGGYGGGGYGGGGGGYGGGGGGYGGGVGGGRGGGGGLGGGRGGGGGLVDGKDDVGLGGGGYGGGLGGGQGGGGGLGGGQGGGGGLGGGRGGGGYGGGGGGYGGGKYGGGKY
Physicochemical Analysis
C393H587N143O141
ANCEHIMFPSTW
G
9570.86
9.86
9
4
19
+5
2.22
-0.597
26.75
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
14900
155.68
12
Residue Composition
number
0
A
6
R
0
N
4
D
0
C
0
E
2
Q
86
G
0
H
0
I
6
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
10
Y
3
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 4 C: 0 E: 0 Q: 2 G: 86 H: 0 I: 0 L: 6 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 10 V: 3
Chemical Descriptors
120
C393H587N143O141
9570.86
9.86
+5
2.22
-0.597
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2-5 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active primarily against E. coli (MIC 2-5 uM) evaluated using a mixture of peptides. This is a bacteriostatic effect. The growth of S.
Evidence 2 Activity

Activity

MIC
Antibacterial
>10 µM

Target

Staphylococcus aureus was inhibited

Source & Reference

NA

Other

uM) evaluated using a mixture of peptides. This is a bacteriostatic effect. The growth of S. aureus was inhibited (MIC >10 uM) and no inhibition was observed against C-albicans up to 5 uM.
Evidence 3 Activity

Activity

MIC
Antifungal
2-5 µM

Target

Escherichia coli

Source & Reference

Antifungipept

Other

Active primarily against E. coli (MIC 2-5 uM) evaluated using a mixture of peptides. This is a bacteriostatic effect. The growth of S.
Evidence 4 Activity

Activity

MIC
Antifungal
>10 µM

Target

Staphylococcus aureus was inhibited

Source & Reference

Antifungipept

Other

uM) evaluated using a mixture of peptides. This is a bacteriostatic effect. The growth of S. aureus was inhibited (MIC >10 uM) and no inhibition was observed against C-albicans up to 5 uM.