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Peptide record

TPDB18613

Antibacterial Antiviral Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB18613
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
DRGWGNGCGLFG
Physicochemical Analysis
C53H75N17O16S1
AEQHIKMPSTYV
G
1238.34
6.09
1
1
3
-0
-1.27
-0.442
32.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
5500
444.14
2
Residue Composition
number
0
A
1
R
1
N
1
D
1
C
0
E
0
Q
5
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 1 C: 1 E: 0 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C53H75N17O16S1
1238.34
6.09
-0
-1.27
-0.442
Evidence Records 3 records
Evidence 1 Activity

Activity

<10% Cell death
Toxicity
50 µM
Cytotoxic
<10% Cell death | 50 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
In vitro analysis of synthetic peptides in blocking the entry of dengue virus. | Virus Res | 2019
Evidence 2 Activity

Activity

20% Cell death
Toxicity
200 µM
Cytotoxic
20% Cell death | 200 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
In vitro analysis of synthetic peptides in blocking the entry of dengue virus. | Virus Res | 2019
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.30508603]<20% cytotoxicity against Vero and C6/36 cells at 200 µM.

Source & Reference

NA
DRAMP
Virus Res. 2019 Jan 15 260:142-150.