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Peptide record

TPDB18576

Antibacterial Anticancer Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB18576
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
DLFKQLQRLFLGILYCLYKIW
Physicochemical Analysis
C132H201N29O28S1
ANEHMPSTV
L
2674.29
9.53
3
1
13
+2
-5.02
0.629
148.57
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
8480
317.09
5
Residue Composition
number
0
A
1
R
0
N
1
D
1
C
0
E
2
Q
1
G
0
H
2
I
6
L
2
K
0
M
2
F
0
P
0
S
0
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 1 E: 0 Q: 2 G: 1 H: 0 I: 2 L: 6 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 0
Chemical Descriptors
21
C132H201N29O28S1
2674.29
9.53
+2
-5.02
0.629
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
132±16 µM
Hemolytic Cytotoxic
50% Hemolysis | 132±16 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designing Anticancer Peptides by Constructive Machine Learning. | ChemMedChem | 2018
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes：50% Hemolysis=132±16 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
ChemMedChem. 2018 Jul 6 13(13):1300-1302.