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Peptide record

TPDB18546

Antibacterial Toxicity standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB18546
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 50-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
DFDPTEFKGPFPTIEICSKYCAVVCNYTSRPCYCVEAAKERDQWFPYCYD
Physicochemical Analysis
C266H378N62O79S6
HLM
C
5900.66
4.29
5
8
18
-3
8.10
-0.440
39.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
13325
225.82
18
Residue Composition
number
3
A
2
R
1
N
4
D
6
C
4
E
1
Q
1
G
0
H
2
I
0
L
3
K
0
M
4
F
5
P
2
S
3
T
1
W
5
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 1 D: 4 C: 6 E: 4 Q: 1 G: 1 H: 0 I: 2 L: 0 K: 3 M: 0 F: 4 P: 5 S: 2 T: 3 W: 1 Y: 5 V: 3
Chemical Descriptors
50
C266H378N62O79S6
5900.66
4.29
-3
8.10
-0.440
Evidence Records 1 records
Evidence 1 Activity

Activity

MIC
Antibacterial
17 µM

Target

Escherichia coli

Source & Reference

NA

Other

Active against E. coli. Loth et al., 2022 refined the MIC E. coli (MIC 17 uM) and gram+ M-luteus (MIC >80 uM).