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Peptide record

TPDB18526

Antibacterial Antifungal Toxicity standard
147 amino acids
Basic Information
3D PDB MODEL
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TPDB18526
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb
standard
No
A 147-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, Antifungipept, and CAFPdb, with an available 3D structural model.
Sequence
DDTRGGFHGGGFGRPGRPGRPGSGILDTIVDGLTGSIHGGQGGIHGGIHGGGHGGHGGVVHGRQCGVNVPTHITTGCKLFTRNLYGQYVCDRNQKPAFRCPPLRAECPLATRFGPPIQCTLDTDCPGISDKCCCDACLDHPVCKPSA
Physicochemical Analysis
C644H1009N207O194S12
MW
G
15140.09
7.87
23
11
35
+3
29.53
-0.361
59.66
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
3730
24.64
36
Residue Composition
number
5
A
10
R
3
N
10
D
12
C
1
E
5
Q
31
G
9
H
8
I
8
L
4
K
0
M
5
F
13
P
4
S
10
T
0
W
2
Y
7
V
Amino Acid Distribution
A: 5 R: 10 N: 3 D: 10 C: 12 E: 1 Q: 5 G: 31 H: 9 I: 8 L: 8 K: 4 M: 0 F: 5 P: 13 S: 4 T: 10 W: 0 Y: 2 V: 7
Chemical Descriptors
147
C644H1009N207O194S12
15140.09
7.87
+3
29.53
-0.361
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.7-1.4 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against Gram+ S. aureus (MIC 0.7-1.4 uM), B. subtilis (MIC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (M
Evidence 2 Activity

Activity

MIC
Antibacterial
0.7-1.4 µM

Target

B. subtilis

Source & Reference

NA

Other

Active against Gram+ S. aureus (MIC 0.7-1.4 uM), B. subtilis (MIC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (MIC 1.4-2.8 uM), V. parahaemoly
Evidence 3 Activity

Activity

MIC
Antibacterial
0.35-0.7 µM

Target

B. megaterium

Source & Reference

NA

Other

Active against Gram+ S. aureus (MIC 0.7-1.4 uM), B. subtilis (MIC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (MIC 1.4-2.8 uM), V. parahaemolyticus (MIC 0.7-1.4 uM), V. harvey
Evidence 4 Activity

Activity

MIC
Antibacterial
1.4-2.8 µM

Target

V. alginolyticus

Source & Reference

NA

Other

us (MIC 0.7-1.4 uM), B. subtilis (MIC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (MIC 1.4-2.8 uM), V. parahaemolyticus (MIC 0.7-1.4 uM), V. harveyi (MIC MIC 0.7-1.4 uM), E. coli (MIC 2.8-
Evidence 5 Activity

Activity

MIC
Antibacterial
0.7-1.4 µM

Target

V. parahaemolyticus

Source & Reference

NA

Other

IC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (MIC 1.4-2.8 uM), V. parahaemolyticus (MIC 0.7-1.4 uM), V. harveyi (MIC MIC 0.7-1.4 uM), E. coli (MIC 2.8-5.6 uM), and fungi C. albicans (MIC 2.
Evidence 6 Activity

Activity

MIC
Antibacterial
2.8-5.6 µM

Target

Escherichia coli

Source & Reference

NA

Other

(MIC 1.4-2.8 uM), V. parahaemolyticus (MIC 0.7-1.4 uM), V. harveyi (MIC MIC 0.7-1.4 uM), E. coli (MIC 2.8-5.6 uM), and fungi C. albicans (MIC 2.8-5.6 uM). In addition, SpCrus2 agglutinates gram-positive
Evidence 7 Activity

Activity

MIC
Antibacterial
2.8-5.6 µM

Target

Candida albicans

Source & Reference

NA

Other

us (MIC 0.7-1.4 uM), V. harveyi (MIC MIC 0.7-1.4 uM), E. coli (MIC 2.8-5.6 uM), and fungi C. albicans (MIC 2.8-5.6 uM). In addition, SpCrus2 agglutinates gram-positive bacteria (bacteria-agglutinating).
Evidence 8 Activity

Activity

MIC
Antifungal
0.7-1.4 µM

Target

Staphylococcus aureus

Source & Reference

CAFPdb Antifungipept

Other

Active against Gram+ S. aureus (MIC 0.7-1.4 uM), B. subtilis (MIC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (M
Evidence 9 Activity

Activity

MIC
Antifungal
0.7-1.4 µM

Target

B. subtilis

Source & Reference

CAFPdb Antifungipept

Other

Active against Gram+ S. aureus (MIC 0.7-1.4 uM), B. subtilis (MIC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (MIC 1.4-2.8 uM), V. parahaemoly
Evidence 10 Activity

Activity

MIC
Antifungal
0.35-0.7 µM

Target

B. megaterium

Source & Reference

CAFPdb Antifungipept

Other

Active against Gram+ S. aureus (MIC 0.7-1.4 uM), B. subtilis (MIC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (MIC 1.4-2.8 uM), V. parahaemolyticus (MIC 0.7-1.4 uM), V. harvey
Evidence 11 Activity

Activity

MIC
Antifungal
1.4-2.8 µM

Target

V. alginolyticus

Source & Reference

CAFPdb Antifungipept

Other

us (MIC 0.7-1.4 uM), B. subtilis (MIC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (MIC 1.4-2.8 uM), V. parahaemolyticus (MIC 0.7-1.4 uM), V. harveyi (MIC MIC 0.7-1.4 uM), E. coli (MIC 2.8-
Evidence 12 Activity

Activity

MIC
Antifungal
0.7-1.4 µM

Target

V. parahaemolyticus

Source & Reference

CAFPdb Antifungipept

Other

IC 0.7-1.4 uM), B. megaterium (MIC 0.35-0.7 uM), Gram- V. alginolyticus (MIC 1.4-2.8 uM), V. parahaemolyticus (MIC 0.7-1.4 uM), V. harveyi (MIC MIC 0.7-1.4 uM), E. coli (MIC 2.8-5.6 uM), and fungi C. albicans (MIC 2.
Evidence 13 Activity

Activity

MIC
Antifungal
2.8-5.6 µM

Target

Escherichia coli

Source & Reference

CAFPdb Antifungipept

Other

(MIC 1.4-2.8 uM), V. parahaemolyticus (MIC 0.7-1.4 uM), V. harveyi (MIC MIC 0.7-1.4 uM), E. coli (MIC 2.8-5.6 uM), and fungi C. albicans (MIC 2.8-5.6 uM). In addition, SpCrus2 agglutinates gram-positive
Evidence 14 Activity

Activity

MIC
Antifungal
2.8-5.6 µM

Target

Candida albicans

Source & Reference

CAFPdb Antifungipept

Other

us (MIC 0.7-1.4 uM), V. harveyi (MIC MIC 0.7-1.4 uM), E. coli (MIC 2.8-5.6 uM), and fungi C. albicans (MIC 2.8-5.6 uM). In addition, SpCrus2 agglutinates gram-positive bacteria (bacteria-agglutinating).