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Peptide record

TPDB18389

Antibacterial Antifungal Toxicity modified_plain modified
27 amino acids
Basic Information
3D PDB MODEL
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TPDB18389
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 27-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
CKGKGAKXSRLMYDXCTGSXRSGKXGS
Physicochemical Analysis
C95H165N33O32S3
NEQHIFPWV
G
2377.74
10.31
6
1
4
+5
5.14
-0.844
18.15
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
1615
67.92
8
Residue Composition
number
1
A
2
R
0
N
1
D
2
C
0
E
0
Q
5
G
0
H
0
I
1
L
4
K
1
M
0
F
0
P
4
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 2 E: 0 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 4 M: 1 F: 0 P: 0 S: 4 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
27
C95H165N33O32S3
2377.74
10.31
+5
5.14
-0.844
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
1420 µM
Hemolytic Cytotoxic
50% Hemolysis | 1420 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrocyclic Antimicrobial Peptides Engineered from ?-Conotoxin. | Curr Pharm Des | 2017
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
1450 µM
Hemolytic Cytotoxic
50% Hemolysis | 1450 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Macrocyclic Antimicrobial Peptides Engineered from ?-Conotoxin. | Curr Pharm Des | 2017