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Peptide record

TPDB18331

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB18331
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
CGRRWGWWRCRL
Physicochemical Analysis
C73H107N27O13S2
ANDEQHIKMFPSTYV
R
1634.95
11.93
4
0
4
+4
-3.33
-1.058
32.50
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
16625
1016.85
2
Residue Composition
number
0
A
4
R
0
N
0
D
2
C
0
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
12
C73H107N27O13S2
1634.95
11.93
+4
-3.33
-1.058
Evidence Records 7 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
1101 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 1101 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
54 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 54 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
21 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 21 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
39 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 39 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
30 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 30 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
9 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 9 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022