Back to search

Peptide record

TPDB18328

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB18328
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
CGKKWWGWKCKL
Physicochemical Analysis
C73H107N19O13S2
ARNDEQHIMFPSTYV
K
1522.89
10.17
4
0
4
+4
-2.61
-0.858
32.50
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
16625
1091.67
2
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
2
G
0
H
0
I
1
L
4
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
12
C73H107N19O13S2
1522.89
10.17
+4
-2.61
-0.858
Evidence Records 7 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>1045 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >1045 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
198 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 198 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
55 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 55 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
439 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 439 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
106 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 106 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022