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Peptide record

TPDB18325

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB18325
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
CGKKPGGWKCKL
Physicochemical Analysis
C58H97N17O13S2
ARNDEQHIMFSTYV
K
1304.63
10.17
4
0
2
+4
1.55
-0.875
32.50
Mammalian: 1.2 hour Yeast: >20 hour E.coli: >10 hour
5625
431.16
2
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
0
Q
3
G
0
H
0
I
1
L
4
K
0
M
0
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 4 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C58H97N17O13S2
1304.63
10.17
+4
1.55
-0.875
Evidence Records 6 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>943 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >943 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>957 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >957 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
>971 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >971 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>942 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >942 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
>956 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >956 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
219 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 219 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis and Antimicrobial Activity of Short Analogues of the Marine Antimicrobial Peptide Turgencin A: Effects of SAR Optimizations, Cys-Cys Cyclization and Lipopeptide Modifications. | Int J Mol Sci | 2022