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Peptide record

TPDB18279

Antibacterial Anticancer Toxicity modified_plain modified
9 amino acids
Basic Information
3D PDB MODEL
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TPDB18279
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 9-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
AWXLFDDGV
Physicochemical Analysis
C44H59N9O13
RNCEQHIKMPSTY
D
922.01
2.92
0
2
5
-2
-1.17
0.478
86.67
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
596.53
0
Residue Composition
number
1
A
0
R
0
N
2
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
9
C44H59N9O13
922.01
2.92
-2
-1.17
0.478
Evidence Records 3 records
Evidence 1 Activity

Activity

8% Hemolysis
Toxicity
1000 µM
Hemolytic Cytotoxic
8% Hemolysis | 1000 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of a bactericidal and proapoptotic peptide from Cycas revoluta seeds with DNA binding properties. | J Cell Biochem | 2012
Evidence 2 Activity

Activity

IC50
Toxicity
4000 µM
Cytotoxic
IC50 | 4000 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Identification and characterization of a bactericidal and proapoptotic peptide from Cycas revoluta seeds with DNA binding properties. | J Cell Biochem | 2012
Evidence 3 Activity

Activity

IC50
Toxicity
4 mM
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 5% Hemolysis=1 mM | Cytotoxicity: NIH 3T3: IC50=4 mM

Target

erythrocytes

Source & Reference

NA
DRAMP
J Cell Biochem. 2012 Jan 113(1):184-93.