Peptide record

TPDB18268

Antibacterial Antiviral Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB18268
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
AWDFGSIGGVFNSIGRAVHQVFGGAFRTL
Physicochemical Analysis
C142H208N40O37
CEKMPY
G
3067.46
10.89
3
1
14
+1
-2.58
0.472
80.69
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
179.30
5
Residue Composition
number
3
A
2
R
1
N
1
D
0
C
0
E
1
Q
6
G
1
H
2
I
1
L
0
K
0
M
4
F
0
P
2
S
1
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 6 H: 1 I: 2 L: 1 K: 0 M: 0 F: 4 P: 0 S: 2 T: 1 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C142H208N40O37
3067.46
10.89
+1
-2.58
0.472
Evidence Records 2 records
Evidence 1 Activity

Activity

25% Cell death
Toxicity
10 µM
Cytotoxic
25% Cell death | 10 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Antiviral activity of peptide inhibitors derived from the protein E stem against Japanese encephalitis and Zika viruses. | Antiviral Res | 2017
Evidence 2 Activity

Activity

12% Cell death
Toxicity
1 µM
Cytotoxic
12% Cell death | 1 | µM | target cell: Baby Hamster Kidney cells BHK-21

Target

Baby Hamster Kidney cells BHK-21

Source & Reference

NA
DBAASP
Antiviral activity of peptide inhibitors derived from the protein E stem against Japanese encephalitis and Zika viruses. | Antiviral Res | 2017