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Peptide record

TPDB18247

Antibacterial Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB18247
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 28-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AVLSFVHKLFLNFLHVDTSKGKCRATLQ
Physicochemical Analysis
C146H234N40O37S1
EIMPWY
L
3173.77
10.32
6
1
13
+3
1.92
0.343
107.86
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
2
A
1
R
1
N
1
D
1
C
0
E
1
Q
1
G
2
H
0
I
5
L
3
K
0
M
3
F
0
P
2
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 1 C: 1 E: 0 Q: 1 G: 1 H: 2 I: 0 L: 5 K: 3 M: 0 F: 3 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
28
C146H234N40O37S1
3173.77
10.32
+3
1.92
0.343
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64-128 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 64-128 ug/ml) and S.aureus ATCC 29213 (MIC 128> ug/ml).
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Mining Amphibian and Insect Transcriptomes for Antimicrobial Peptide Sequences with rAMPage. | Antibiotics (Basel) | 2022