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Peptide record

TPDB18239

Antibacterial Antifungal Toxicity standard
71 amino acids
Basic Information
3D PDB MODEL
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TPDB18239
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 71-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
AVDFSSCARMDVPGLSKVAQGLCISSCKFQNCGTGHCEKRGGRPTCVCDRCGRGGGEWPSVPMPKGRSSRG
Physicochemical Analysis
C304H496N102O95S10
Y
G
7420.51
8.76
12
5
16
+6
15.51
-0.449
41.13
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
6000
80.86
21
Residue Composition
number
3
A
7
R
1
N
3
D
8
C
2
E
2
Q
12
G
1
H
1
I
2
L
4
K
2
M
2
F
5
P
8
S
2
T
1
W
0
Y
5
V
Amino Acid Distribution
A: 3 R: 7 N: 1 D: 3 C: 8 E: 2 Q: 2 G: 12 H: 1 I: 1 L: 2 K: 4 M: 2 F: 2 P: 5 S: 8 T: 2 W: 1 Y: 0 V: 5
Chemical Descriptors
71
C304H496N102O95S10
7420.51
8.76
+6
15.51
-0.449
Evidence Records 2 records
Evidence 1 Activity

Activity

4% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
4% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In vitro antimicrobial properties of recombinant ASABF, an antimicrobial peptide isolated from the nematode Ascaris suum. | Antimicrob Agents Chemother | 2000
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In vitro antimicrobial properties of recombinant ASABF, an antimicrobial peptide isolated from the nematode Ascaris suum. | Antimicrob Agents Chemother | 2000