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Peptide record

TPDB18231

Antibacterial Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB18231
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
ATPKMEQFLQKLMKRMARLKASAV
Physicochemical Analysis
C122H214N36O31S3
NDCGHIWY
AK
2777.44
11.63
6
1
12
+5
5.37
-0.287
77.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
4
A
2
R
0
N
0
D
0
C
1
E
2
Q
0
G
0
H
0
I
3
L
4
K
3
M
1
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 2 G: 0 H: 0 I: 0 L: 3 K: 4 M: 3 F: 1 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
24
C122H214N36O31S3
2777.44
11.63
+5
5.37
-0.287
Evidence Records 1 records
Evidence 1 Activity

Activity

<7% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
<7% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
LcCCL28-25, Derived from Piscine Chemokine, Exhibits Antimicrobial Activity against Gram-Negative and Gram-Positive Bacteria In Vitro and In Vivo | Microbiol Spectr | 2022