Peptide record

TPDB18206

Antibacterial standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB18206
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 39-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
ATCDLLSATKVKSTACAAHCLLKGHKGGYCNSKLVCVCR
Physicochemical Analysis
C170H290N52O50S6
EQIMFPW
C
4054.85
8.88
8
1
14
+5
4.35
0.287
85.13
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1865
45.99
14
Residue Composition
number
5
A
1
R
1
N
1
D
6
C
0
E
0
Q
3
G
2
H
0
I
5
L
5
K
0
M
0
F
0
P
3
S
3
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 5 R: 1 N: 1 D: 1 C: 6 E: 0 Q: 0 G: 3 H: 2 I: 0 L: 5 K: 5 M: 0 F: 0 P: 0 S: 3 T: 3 W: 0 Y: 1 V: 3
Chemical Descriptors
39
C170H290N52O50S6
4054.85
8.88
+5
4.35
0.287
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
30-60 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

both deffusion and microdilution methods were used. Active against E. coli (MIC 30-60 ug/ml) and S. aureus (MIC 15-30 ug/ml) but not Salmonella spp. (MIC > 100 ug/ml). Warning: activ
Evidence 2 Activity

Activity

MIC
Antibacterial
15-30 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

ffusion and microdilution methods were used. Active against E. coli (MIC 30-60 ug/ml) and S. aureus (MIC 15-30 ug/ml) but not Salmonella spp. (MIC > 100 ug/ml). Warning: activity was tested using the TRX fus