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Peptide record

TPDB18199

Antibacterial standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB18199
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 43-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
ATCDALSFQSKWITINHSACAIHCIAKGYKGGQCKNTVCHCRK
Physicochemical Analysis
C200H320N62O57S6
EMP
C
4697.48
8.88
9
1
14
+5
4.77
-0.144
63.72
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
7365
156.79
17
Residue Composition
number
5
A
1
R
2
N
1
D
6
C
0
E
2
Q
3
G
3
H
4
I
1
L
5
K
0
M
1
F
0
P
3
S
3
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 5 R: 1 N: 2 D: 1 C: 6 E: 0 Q: 2 G: 3 H: 3 I: 4 L: 1 K: 5 M: 0 F: 1 P: 0 S: 3 T: 3 W: 1 Y: 1 V: 1
Chemical Descriptors
43
C200H320N62O57S6
4697.48
8.88
+5
4.77
-0.144
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.92 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

NA

Other

ducted using both agar diffusion and microdilution assays. CcDef2 is active against Gram+ S. aureus ATCC 25923 (MIC 0.92 uM), M. luteus CMCC 28001 (MIC 1.24 uM), and B. subtilis CMCC 63501 (MIC 1.56uM), but NOT Gra
Evidence 2 Activity

Activity

MIC
Antibacterial
1.24 µM

Target

M. luteus CMCC 28001

Source & Reference

NA

Other

microdilution assays. CcDef2 is active against Gram+ S. aureus ATCC 25923 (MIC 0.92 uM), M. luteus CMCC 28001 (MIC 1.24 uM), and B. subtilis CMCC 63501 (MIC 1.56uM), but NOT Gram- bacteria, i.e., P.aeruginosa, E.c
Evidence 3 Activity

Activity

MIC
Antibacterial
1.56 µM

Target

B. subtilis CMCC 63501

Source & Reference

NA

Other

against Gram+ S. aureus ATCC 25923 (MIC 0.92 uM), M. luteus CMCC 28001 (MIC 1.24 uM), and B. subtilis CMCC 63501 (MIC 1.56uM), but NOT Gram- bacteria, i.e., P.aeruginosa, E.coli, and S.typhi at the tested concentrat