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Peptide record

TPDB18180

Antibacterial standard
47 amino acids
Basic Information
3D PDB MODEL
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TPDB18180
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 47-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
ASPAIWGCDSFLGYCRLACFARESSVGQKECAEGMLCCIPNVFGTFW
Physicochemical Analysis
C227H336N58O64S7
H
C
5125.94
4.65
3
4
20
-1
-1.33
0.421
64.47
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
12865
250.98
14
Residue Composition
number
5
A
2
R
1
N
1
D
6
C
3
E
1
Q
5
G
0
H
2
I
3
L
1
K
1
M
4
F
2
P
4
S
1
T
2
W
1
Y
2
V
Amino Acid Distribution
A: 5 R: 2 N: 1 D: 1 C: 6 E: 3 Q: 1 G: 5 H: 0 I: 2 L: 3 K: 1 M: 1 F: 4 P: 2 S: 4 T: 1 W: 2 Y: 1 V: 2
Chemical Descriptors
47
C227H336N58O64S7
5125.94
4.65
-1
-1.33
0.421
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.75 µg/mL

Target

V. vulnificus ATCC 279562

Source & Reference

NA

Other

Active against V. vulnificus ATCC 279562 (MIC 3.75 ug/ml), V. harveyi ATCC33866 (MIC 50 ug/ml) in TSB medum, A. hydrophila ATCC7966 (MIC 100 ug/ml)
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

V. harveyi ATCC33866

Source & Reference

NA

Other

Active against V. vulnificus ATCC 279562 (MIC 3.75 ug/ml), V. harveyi ATCC33866 (MIC 50 ug/ml) in TSB medum, A. hydrophila ATCC7966 (MIC 100 ug/ml) in LB medum, S. iniae ATCC29178E (MI
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

A. hydrophila ATCC7966

Source & Reference

NA

Other

ulnificus ATCC 279562 (MIC 3.75 ug/ml), V. harveyi ATCC33866 (MIC 50 ug/ml) in TSB medum, A. hydrophila ATCC7966 (MIC 100 ug/ml) in LB medum, S. iniae ATCC29178E (MIC 50 ug/ml) in BHI medium, inactive: E.coli K12 (MIC
Evidence 4 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

S. iniae ATCC29178E

Source & Reference

NA

Other

TCC33866 (MIC 50 ug/ml) in TSB medum, A. hydrophila ATCC7966 (MIC 100 ug/ml) in LB medum, S. iniae ATCC29178E (MIC 50 ug/ml) in BHI medium, inactive: E.coli K12 (MIC >100 ug/ml) and L. monocytogenes ATCC19115 (MIC
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli K12

Source & Reference

NA

Other

(MIC 100 ug/ml) in LB medum, S. iniae ATCC29178E (MIC 50 ug/ml) in BHI medium, inactive: E.coli K12 (MIC >100 ug/ml) and L. monocytogenes ATCC19115 (MIC >100 ug/ml). In addition, QS-BD treatment promoted re
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

L. monocytogenes ATCC19115

Source & Reference

NA

Other

iniae ATCC29178E (MIC 50 ug/ml) in BHI medium, inactive: E.coli K12 (MIC >100 ug/ml) and L. monocytogenes ATCC19115 (MIC >100 ug/ml). In addition, QS-BD treatment promoted respiratory bursts and upregulated the expression