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Peptide record

TPDB18162

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB18162
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
ARKKWRKRLKKLKI
Physicochemical Analysis
C86H158N30O15
NDCEQGHMFPSTYV
K
1852.39
12.72
9
0
5
+9
4.92
-1.707
90.71
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
296.91
0
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
6
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C86H158N30O15
1852.39
12.72
+9
4.92
-1.707
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021