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Peptide record

TPDB18110

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB18110
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
APLKMKAILEIVHRRMKQNKMKAAF
Physicochemical Analysis
C132H230N40O30S3
DCGSTWY
K
2953.71
11.68
8
1
13
+6
6.83
-0.292
90.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
4
A
2
R
1
N
0
D
0
C
1
E
1
Q
0
G
1
H
2
I
2
L
5
K
3
M
1
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 2 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 1 I: 2 L: 2 K: 5 M: 3 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
25
C132H230N40O30S3
2953.71
11.68
+6
6.83
-0.292
Evidence Records 1 records
Evidence 1 Activity

Activity

<7% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
<7% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
LcCCL28-25, Derived from Piscine Chemokine, Exhibits Antimicrobial Activity against Gram-Negative and Gram-Positive Bacteria In Vitro and In Vivo | Microbiol Spectr | 2022