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Peptide record

TPDB18062

Antibacterial Anticancer Antifungal Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB18062
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0 CAFPdb ToxinPred 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CancerPPD 2.0, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ALWKDLLKNVGIAAGKAALNKVTDMVNQ
Physicochemical Analysis
C133H225N37O38S1
RCEHFPSY
A
2982.53
10.16
4
2
15
+2
3.15
0.150
118.57
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
184.41
5
Residue Composition
number
5
A
0
R
3
N
2
D
0
C
0
E
1
Q
2
G
0
H
1
I
4
L
4
K
1
M
0
F
0
P
0
S
1
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 5 R: 0 N: 3 D: 2 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 4 K: 4 M: 1 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 3
Chemical Descriptors
28
C133H225N37O38S1
2982.53
10.16
+2
3.15
0.150
Evidence Records 3 records
Evidence 1 Activity

Activity

10.65% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
10.65% Hemolysis | 128 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
In vitro activities of a novel antimicrobial peptide isolated from phyllomedusa tomopterna. | Microb Pathog | 2021
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
436.7 µM
Hemolytic Cytotoxic
50% Hemolysis | 436.7 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
In vitro activities of a novel antimicrobial peptide isolated from phyllomedusa tomopterna. | Microb Pathog | 2021
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Microb Pathog. 2021 Apr 153:104795.