Back to search

Peptide record

TPDB18056

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB18056
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ALQGAKERAHQQ
Physicochemical Analysis
C55H93N21O18
NDCIMFPSTWYV
AQ
1336.47
10.09
3
1
4
+1
5.46
-1.400
57.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
3
A
1
R
0
N
0
D
0
C
1
E
3
Q
1
G
1
H
0
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 3 G: 1 H: 1 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C55H93N21O18
1336.47
10.09
+1
5.46
-1.400
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
390 µM
Hemolytic Cytotoxic
5% Hemolysis | 390 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular Design, Structural Analysis and Antifungal Activity of Derivatives of Peptide CGA-N46. | Interdiscip Sci | 2016
Evidence 2 Activity

Activity

5% Hemolysis
Toxicity
519.29 ± 6.71 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 519.29 ± 6.71 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design, synthesis, antifungal evaluation and docking studies of antifungal peptide CGA-N12 analogues based on the target CtKRE9. | Bioorg Chem | 2022