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Peptide record

TPDB18055

Antibacterial Antifungal standard
45 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB18055
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 45-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
ALQFIQNTASGALYYNTKTHKYQYQQTSGAMGAAINVFNQQGINW
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C226H336N62O68S1
RDCEP
Q
5041.59
9.71
3
0
20
+2
1.14
-0.478
63.11
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
11460
2.27
22
Residue Composition
number
6
A
0
R
5
N
0
D
0
C
0
E
7
Q
4
G
1
H
3
I
2
L
2
K
1
M
2
F
0
P
2
S
4
T
1
W
4
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 5 D: 0 C: 0 E: 0 Q: 7 G: 4 H: 1 I: 3 L: 2 K: 2 M: 1 F: 2 P: 0 S: 2 T: 4 W: 1 Y: 4 V: 1
Chemical Descriptors
45 reviewed residue count
C226H336N62O68S1 sequence-only estimate (linear, free termini)
5041.59 sequence-only estimate (linear, free termini)
9.71 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
1.14 sequence-only estimate (linear, free termini)
-0.478 sequence-only estimate (linear, free termini)
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.156 µM

Target

p. cremoris ATCC 19257T or NZ9000

Source & Reference

NA

Other

lactis (strains ATCC 19435T, IL1430, JCM 7638, QU4, Qu5) (MIC 0.156-0.31 uM), L. lactis ssp. cremoris ATCC 19257T or NZ9000 (MIC 0.156 uM), L. lactis ssp. hordniae JCM 1180T (MIC 0.156 uM), L. garvieae NCFB 2155T (MIC 10 uM), L.
Evidence 2 Activity

Activity

MIC
Antibacterial
0.156 µM

Target

p. hordniae JCM 1180T

Source & Reference

NA

Other

0.156-0.31 uM), L. lactis ssp. cremoris ATCC 19257T or NZ9000 (MIC 0.156 uM), L. lactis ssp. hordniae JCM 1180T (MIC 0.156 uM), L. garvieae NCFB 2155T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus
Evidence 3 Activity

Activity

MIC
Antibacterial
10 µM

Target

L. garvieae NCFB 2155T

Source & Reference

NA

Other

s ATCC 19257T or NZ9000 (MIC 0.156 uM), L. lactis ssp. hordniae JCM 1180T (MIC 0.156 uM), L. garvieae NCFB 2155T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis J
Evidence 4 Activity

Activity

MIC
Antibacterial
20 µM

Target

L. raffinolactis JCM 5706T

Source & Reference

NA

Other

M), L. lactis ssp. hordniae JCM 1180T (MIC 0.156 uM), L. garvieae NCFB 2155T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2
Evidence 5 Activity

Activity

MIC
Antibacterial
10 µM

Target

p. QU 12

Source & Reference

NA

Other

L. garvieae NCFB 2155T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JC
Evidence 6 Activity

Activity

MIC
Antibacterial
20 µM

Target

B. subtilis JCM 1465T

Source & Reference

NA

Other

T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JCM 5885 (MIC 10 uM), L. sakei ssp. s
Evidence 7 Activity

Activity

MIC
Antibacterial
20 µM

Target

B. circulans JCM 2504T

Source & Reference

NA

Other

5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JCM 5885 (MIC 10 uM), L. sakei ssp. sakei JCM 1157T (MIC 10 uM), and L. m
Evidence 8 Activity

Activity

MIC
Antibacterial
10 µM

Target

P. pentosaceus JCM 5885

Source & Reference

NA

Other

QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JCM 5885 (MIC 10 uM), L. sakei ssp. sakei JCM 1157T (MIC 10 uM), and L. mesenteroides ssp. mesenteroides JCM 6
Evidence 9 Activity

Activity

MIC
Antibacterial
10 µM

Target

p. sakei JCM 1157T

Source & Reference

NA

Other

uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JCM 5885 (MIC 10 uM), L. sakei ssp. sakei JCM 1157T (MIC 10 uM), and L. mesenteroides ssp. mesenteroides JCM 6124T (MIC 10 uM). Update: The orginal incom
Evidence 10 Activity

Activity

MIC
Antibacterial
10 µM

Target

p. mesenteroides JCM 6124T

Source & Reference

NA

Other

s JCM 5885 (MIC 10 uM), L. sakei ssp. sakei JCM 1157T (MIC 10 uM), and L. mesenteroides ssp. mesenteroides JCM 6124T (MIC 10 uM). Update: The orginal incomplete sequence of Serracin-P 23 kDa subunit was replaced 7/2019
Evidence 11 Activity

Activity

MIC
Antifungal
0.156 µM

Target

p. cremoris ATCC 19257T or NZ9000

Source & Reference

Antifungipept

Other

lactis (strains ATCC 19435T, IL1430, JCM 7638, QU4, Qu5) (MIC 0.156-0.31 uM), L. lactis ssp. cremoris ATCC 19257T or NZ9000 (MIC 0.156 uM), L. lactis ssp. hordniae JCM 1180T (MIC 0.156 uM), L. garvieae NCFB 2155T (MIC 10 uM), L.
Evidence 12 Activity

Activity

MIC
Antifungal
0.156 µM

Target

p. hordniae JCM 1180T

Source & Reference

Antifungipept

Other

0.156-0.31 uM), L. lactis ssp. cremoris ATCC 19257T or NZ9000 (MIC 0.156 uM), L. lactis ssp. hordniae JCM 1180T (MIC 0.156 uM), L. garvieae NCFB 2155T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus
Evidence 13 Activity

Activity

MIC
Antifungal
10 µM

Target

L. garvieae NCFB 2155T

Source & Reference

Antifungipept

Other

s ATCC 19257T or NZ9000 (MIC 0.156 uM), L. lactis ssp. hordniae JCM 1180T (MIC 0.156 uM), L. garvieae NCFB 2155T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis J
Evidence 14 Activity

Activity

MIC
Antifungal
20 µM

Target

L. raffinolactis JCM 5706T

Source & Reference

Antifungipept

Other

M), L. lactis ssp. hordniae JCM 1180T (MIC 0.156 uM), L. garvieae NCFB 2155T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2
Evidence 15 Activity

Activity

MIC
Antifungal
10 µM

Target

p. QU 12

Source & Reference

Antifungipept

Other

L. garvieae NCFB 2155T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JC
Evidence 16 Activity

Activity

MIC
Antifungal
20 µM

Target

B. subtilis JCM 1465T

Source & Reference

Antifungipept

Other

T (MIC 10 uM), L. raffinolactis JCM 5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JCM 5885 (MIC 10 uM), L. sakei ssp. s
Evidence 17 Activity

Activity

MIC
Antifungal
20 µM

Target

B. circulans JCM 2504T

Source & Reference

Antifungipept

Other

5706T (MIC 20 uM), Lactococcus sp. QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JCM 5885 (MIC 10 uM), L. sakei ssp. sakei JCM 1157T (MIC 10 uM), and L. m
Evidence 18 Activity

Activity

MIC
Antifungal
10 µM

Target

P. pentosaceus JCM 5885

Source & Reference

Antifungipept

Other

QU 12 (MIC 10 uM), B. subtilis JCM 1465T (MIC 20 uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JCM 5885 (MIC 10 uM), L. sakei ssp. sakei JCM 1157T (MIC 10 uM), and L. mesenteroides ssp. mesenteroides JCM 6
Evidence 19 Activity

Activity

MIC
Antifungal
10 µM

Target

p. sakei JCM 1157T

Source & Reference

Antifungipept

Other

uM), B. circulans JCM 2504T (MIC 20 uM), P. pentosaceus JCM 5885 (MIC 10 uM), L. sakei ssp. sakei JCM 1157T (MIC 10 uM), and L. mesenteroides ssp. mesenteroides JCM 6124T (MIC 10 uM). Update: The orginal incom
Evidence 20 Activity

Activity

MIC
Antifungal
10 µM

Target

p. mesenteroides JCM 6124T

Source & Reference

Antifungipept

Other

s JCM 5885 (MIC 10 uM), L. sakei ssp. sakei JCM 1157T (MIC 10 uM), and L. mesenteroides ssp. mesenteroides JCM 6124T (MIC 10 uM). Update: The orginal incomplete sequence of Serracin-P 23 kDa subunit was replaced 7/2019