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Peptide record

TPDB18053

Antibacterial Anticancer Antifungal Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB18053
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb
standard
No
A 16-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, Antifungipept, and CAFPdb, with an available 3D structural model.
Sequence
ALRGCWTKSIPPKPCK
Physicochemical Analysis
C80H133N23O19S2
NDEQHMFYV
KP
1785.20
10.32
4
0
4
+4
2.04
-0.544
55.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5625
315.09
4
Residue Composition
number
1
A
1
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
1
I
1
L
3
K
0
M
0
F
3
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 3 M: 0 F: 0 P: 3 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C80H133N23O19S2
1785.20
10.32
+4
2.04
-0.544
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
512 µM
Hemolytic Cytotoxic
10% Hemolysis | 512 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor. | Biomolecules | 2019
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human microvascular endothelial cells HMEC-1

Target

Human microvascular endothelial cells HMEC-1

Source & Reference

NA
DBAASP
Discovery and Rational Design of a Novel Bowman-Birk Related Protease Inhibitor. | Biomolecules | 2019