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Peptide record

TPDB18046

Antibacterial Toxicity modified_plain modified
26 amino acids
Basic Information
3D PDB MODEL
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TPDB18046
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 26-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
ALALLXHALHXLALLAXHLAHXLALA
Physicochemical Analysis
C108H180N30O23
RNDCEQGIKMFPSTWYV
L
2266.80
8.15
4
0
18
+0
-3.12
1.523
180.77
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
8
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
4
H
0
I
10
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 4 I: 0 L: 10 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
26
C108H180N30O23
2266.80
8.15
+0
-3.12
1.523
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
<5.6 µM
Hemolytic Cytotoxic
50% Hemolysis | <5.6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structural determinants of antimicrobial and antiplasmodial activity and selectivity in histidine-rich amphipathic cationic peptides. | J Biol Chem | 2009