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Peptide record

TPDB18034

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB18034
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AKKVVKKIYKRFQK
Physicochemical Analysis
C84H146N24O17
NDCEGHLMPSTW
K
1764.23
11.22
7
0
6
+7
4.92
-1.086
76.43
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
84.46
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
0
L
6
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 6 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
14
C84H146N24O17
1764.23
11.22
+7
4.92
-1.086
Evidence Records 1 records
Evidence 1 Activity

Activity

20% Hemolysis
Toxicity
>2000 µg/mL
Hemolytic Cytotoxic
20% Hemolysis | >2000 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Machine learning designs non-hemolytic antimicrobial peptides. | Chem Sci | 2021