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Peptide record

TPDB18030

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
55 amino acids
Basic Information
3D PDB MODEL
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TPDB18030
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia ACP740 _ACP240 AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP dbAMP 3.0
standard
No
A 55-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, ACP740 _ACP240, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
AKYTGKCTKSKNECKYKNDAGKDTFIKCPKFDNKKCTKDNNKCTVDTYNNAVDCD
Physicochemical Analysis
C263H421N75O89S6
RQHLMW
K
6250.05
8.80
13
8
11
+5
20.68
-1.375
23.09
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
4845
77.52
23
Residue Composition
number
3
A
0
R
7
N
7
D
6
C
1
E
0
Q
2
G
0
H
1
I
0
L
13
K
0
M
2
F
1
P
1
S
6
T
0
W
3
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 7 D: 7 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 1 L: 0 K: 13 M: 0 F: 2 P: 1 S: 1 T: 6 W: 0 Y: 3 V: 2
Chemical Descriptors
55
C263H421N75O89S6
6250.05
8.80
+5
20.68
-1.375
Evidence Records 4 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The Evolutionary Conserved ?-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF. | Front Microbiol | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human Primary Epidermal Keratinocytes (HEK)

Target

Human Primary Epidermal Keratinocytes (HEK)

Source & Reference

NA
DBAASP
The Evolutionary Conserved ?-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF. | Front Microbiol | 2018
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human fibroblasts

Target

Human fibroblasts

Source & Reference

NA
DBAASP
The Evolutionary Conserved ?-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF. | Front Microbiol | 2018
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human normal embryonic lung cells L132

Target

Human normal embryonic lung cells L132

Source & Reference

NA
DBAASP
New Antimicrobial Potential and Structural Properties of PAFB: A Cationic, Cysteine-Rich Protein from Penicillium chrysogenum Q176. | Sci Rep | 2018