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Peptide record

TPDB18010

Antibacterial Antifungal standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB18010
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 12-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
AKRHHKYKRKFH
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C75H118N28O14
NDCEQGILMPSTWV
K
1635.94
11.65
9
0
3
+6
5.11
-2.575
8.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
0.91
1
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
3
H
0
I
0
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 3 I: 0 L: 0 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12 reviewed residue count
C75H118N28O14 sequence-only estimate (linear, free termini)
1635.94 sequence-only estimate (linear, free termini)
11.65 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
5.11 sequence-only estimate (linear, free termini)
-2.575 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against C. albicans (LD50 5.6 ug/ml LD90 10 ug/ml).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against C. albicans (LD50 5.6 ug/ml LD90 10 ug/ml).