Back to search

Peptide record

TPDB18004

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB18004
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AKKRAKKRAHQQ
Physicochemical Analysis
C61H112N26O15
NDCEGILMFPSTWYV
K
1449.73
12.44
7
0
3
+6
7.19
-2.450
25.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
3
A
2
R
0
N
0
D
0
C
0
E
2
Q
0
G
1
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 1 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C61H112N26O15
1449.73
12.44
+6
7.19
-2.450
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
711.86 ± 47.18 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 711.86 ± 47.18 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design, synthesis, antifungal evaluation and docking studies of antifungal peptide CGA-N12 analogues based on the target CtKRE9. | Bioorg Chem | 2023