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Peptide record

TPDB17999

Antibacterial Antiviral Toxicity standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB17999
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AVPpred-BWR DRAVP 2.0
standard
No
A 21-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AVPpred-BWR, and DRAVP 2.0, with an available 3D structural model.
Sequence
AKKAAKKAKKAAKKIEKAAKK
Physicochemical Analysis
C101H192N32O24
RNDCQGHLMFPSTWYV
K
2238.84
11.16
11
1
9
+10
11.24
-1.310
56.67
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
8
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
1
I
0
L
11
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 8 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 11 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
21
C101H192N32O24
2238.84
11.16
+10
11.24
-1.310
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Prediction of activity, synthesis and biological testing of anti-HSV active peptides. | Chem Biol Drug Des | 2006
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.16923027]No cytotoxicity against Human fibroblasts MRC-5 cells up to 448 µM.

Source & Reference

NA
DRAMP
Chem Biol Drug Des. 2006 Jul 68(1):58-66.