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Peptide record

TPDB17991

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB17991
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
AKRHHGLNCAKFH
Physicochemical Analysis
C66H103N25O15S1
DEQIMPSTWYV
H
1518.76
10.59
6
0
4
+3
3.83
-1.008
45.38
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
1
R
1
N
0
D
1
C
0
E
0
Q
1
G
3
H
0
I
1
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 1 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 1 H: 3 I: 0 L: 1 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C66H103N25O15S1
1518.76
10.59
+3
3.83
-1.008
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antifungal Activity and Action Mechanism of Histatin 5-Halocidin Hybrid Peptides against Candida ssp. | PLoS One | 2016
Evidence 2 Activity

Activity

50% Cell death
Toxicity
>200 µg/mL
Cytotoxic
50% Cell death | >200 | µg/mL | target cell: Mouse fibroblasts L929

Target

Mouse fibroblasts L929

Source & Reference

NA
DBAASP
Antifungal Activity and Action Mechanism of Histatin 5-Halocidin Hybrid Peptides against Candida ssp. | PLoS One | 2016