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Peptide record

TPDB17944

Antibacterial Antifungal Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB17944
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
AIQRCC
Physicochemical Analysis
C26H48N10O8S2
NDEGHLKMFPSTWYV
C
692.85
8.30
1
0
2
+1
0.43
0.550
81.67
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
125
18.04
3
Residue Composition
number
1
A
1
R
0
N
0
D
2
C
0
E
1
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C26H48N10O8S2
692.85
8.30
+1
0.43
0.550
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
280 µM
Hemolytic Cytotoxic
0% Hemolysis | 280 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Mo-CBP3-PepI, Mo-CBP3-PepII, and Mo-CBP3-PepIII are synthetic antimicrobial peptides active against human pathogens by stimulating ROS generation and increasing plasma membrane permeability | Biochimie | 2019