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Peptide record

TPDB17935

Antibacterial Anticancer Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB17935
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AHPKWMEVVRSRQRKKKHNKRRATY
Physicochemical Analysis
C139H232N52O33S1
DCGILF
RK
3191.76
12.26
12
1
7
+9
11.44
-2.012
31.20
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
6990
219.00
5
Residue Composition
number
2
A
5
R
1
N
0
D
0
C
1
E
1
Q
0
G
2
H
0
I
0
L
5
K
1
M
0
F
1
P
1
S
1
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 5 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 2 I: 0 L: 0 K: 5 M: 1 F: 0 P: 1 S: 1 T: 1 W: 1 Y: 1 V: 2
Chemical Descriptors
25
C139H232N52O33S1
3191.76
12.26
+9
11.44
-2.012
Evidence Records 2 records
Evidence 1 Activity

Activity

<7% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
<7% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
LcCCL28-25, Derived from Piscine Chemokine, Exhibits Antimicrobial Activity against Gram-Negative and Gram-Positive Bacteria In Vitro and In Vivo | Microbiol Spectr | 2022
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
LcCCL28-25, Derived from Piscine Chemokine, Exhibits Antimicrobial Activity against Gram-Negative and Gram-Positive Bacteria In Vitro and In Vivo | Microbiol Spectr | 2022