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Peptide record

TPDB17934

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB17934
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AHPKVKRKLKRMQRKKDGKQKRH
Physicochemical Analysis
C124H225N49O28S1
NCEIFSTWY
K
2882.52
12.44
14
1
4
+11
15.04
-2.452
33.91
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
4
R
0
N
1
D
0
C
0
E
2
Q
1
G
2
H
0
I
1
L
8
K
1
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 2 G: 1 H: 2 I: 0 L: 1 K: 8 M: 1 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C124H225N49O28S1
2882.52
12.44
+11
15.04
-2.452
Evidence Records 1 records
Evidence 1 Activity

Activity

<7% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
<7% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
LcCCL28-25, Derived from Piscine Chemokine, Exhibits Antimicrobial Activity against Gram-Negative and Gram-Positive Bacteria In Vitro and In Vivo | Microbiol Spectr | 2022