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Peptide record

TPDB17925

Antibacterial Antiparasitic Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB17925
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AGWKEWLNKAKDFIKEKGLGMLSAAANAALN
Physicochemical Analysis
C152H241N41O42S1
RCQHPTYV
A
3346.89
10.05
5
3
16
+2
2.84
-0.235
85.48
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
11000
328.66
4
Residue Composition
number
7
A
0
R
3
N
1
D
0
C
2
E
0
Q
3
G
0
H
1
I
4
L
5
K
1
M
1
F
0
P
1
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 7 R: 0 N: 3 D: 1 C: 0 E: 2 Q: 0 G: 3 H: 0 I: 1 L: 4 K: 5 M: 1 F: 1 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
31
C152H241N41O42S1
3346.89
10.05
+2
2.84
-0.235
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
50% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
16.9 µM
Cytotoxic
50% Cytotoxicity | 16.9 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021