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Peptide record

TPDB17916

Antibacterial Antiparasitic Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB17916
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AGTKDWLNKAKDFIKEKGLGILSAAANAAIN
Physicochemical Analysis
C145H238N40O43
RCQHMPYV
A
3229.73
10.05
5
3
15
+2
4.21
-0.123
98.06
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5500
170.29
5
Residue Composition
number
7
A
0
R
3
N
2
D
0
C
1
E
0
Q
3
G
0
H
3
I
3
L
5
K
0
M
1
F
0
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 7 R: 0 N: 3 D: 2 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 3 L: 3 K: 5 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
31
C145H238N40O43
3229.73
10.05
+2
4.21
-0.123
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
>250 µM
Cytotoxic
50% Cytotoxicity | >250 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021