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Peptide record

TPDB17911

Antibacterial Toxicity modified_plain modified
21 amino acids
Basic Information
3D PDB MODEL
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TPDB17911
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 21-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
AGYLLGKINLKKLAKLXKKIL
Physicochemical Analysis
C107H193N27O23
RDCEQHMFPSTWV
LK
2225.88
10.87
6
0
11
+6
1.12
0.305
158.10
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
66.94
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
6
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 6 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
21
C107H193N27O23
2225.88
10.87
+6
1.12
0.305
Evidence Records 2 records
Evidence 1 Activity

Activity

80% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
80% Hemolysis | 512 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria. | J Pept Sci | 2015
Evidence 2 Activity

Activity

100% Killing
Toxicity
32 µg/mL
Cytotoxic
100% Killing | 32 | µg/mL | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Antimicrobial activities and action mechanism studies of transportan 10 and its analogues against multidrug-resistant bacteria. | J Pept Sci | 2015