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Peptide record

TPDB17887

Antibacterial Anticancer Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB17887
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from Peptipedia and PD_Hemolysis, with an available 3D structural model.
Sequence
AFLYRLTRQIRPWWRWLYKW
Physicochemical Analysis
C142H200N38O25
NDCEGHMSV
RW
2839.39
11.96
5
0
12
+5
-7.17
-0.670
83.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
24980
879.77
4
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
3
L
1
K
0
M
1
F
1
P
0
S
1
T
4
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 3 K: 1 M: 0 F: 1 P: 1 S: 0 T: 1 W: 4 Y: 2 V: 0
Chemical Descriptors
20
C142H200N38O25
2839.39
11.96
+5
-7.17
-0.670
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
34±5 µM
Hemolytic Cytotoxic
50% Hemolysis | 34±5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designing Anticancer Peptides by Constructive Machine Learning. | ChemMedChem | 2018
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 50% Hemolysis=34±5 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
ChemMedChem. 2018 Jul 6 13(13):1300-1302.
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis