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Peptide record

TPDB17878

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB17878
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AFVRILCYCCPRRIKRR
Physicochemical Analysis
C94H161N33O19S3
NDEQGHMSTW
R
2153.70
11.18
6
0
7
+6
1.42
-0.012
91.76
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1615
74.99
4
Residue Composition
number
1
A
5
R
0
N
0
D
3
C
0
E
0
Q
0
G
0
H
2
I
1
L
1
K
0
M
1
F
1
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 1 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
17
C94H161N33O19S3
2153.70
11.18
+6
1.42
-0.012
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64-128 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 64-128 ug/ml) and S.aureus ATCC 29213 (MIC >128 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.aureus ATCC 29213

Source & Reference

NA

Other

active against E. coli ATCC 25922 (MIC 64-128 ug/ml) and S.aureus ATCC 29213 (MIC >128 ug/ml).
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Mining Amphibian and Insect Transcriptomes for Antimicrobial Peptide Sequences with rAMPage. | Antibiotics (Basel) | 2022