TPDB

3D PDB MODEL

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TPDB ID TPDB17874

Activity

Antibacterial Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Peptipedia CAFPdb

Sequence_Type

modified_plain

Has_Modification Yes

Description A 251-aa modified multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.

Modification

Modified, details unspecified

Sequence

AEETSFVFSKFKPLEPNLILQGDALVTVAGVLQLTNVDKNGVPEPSSLGRATYSAPINIWDSATGLVASFATSFRFTIYAPNIATIADGLAFFLAPVASAPDSGGGFLGLFDSAVSGSTYQTVAVEFDTYENTVFTDPPYTHIGFDVNSISSIKTVKWSLANGEAAKVLITYNSAVKLLVASLVYPSSKTSFILADIVDLSSVLPEWVRVGFSAATGASGGKIETHDVFSWSFASKLAGXXTKDSSFLDGG

FASTA

>TPDB17874|Antibacterial;Antifungal|length=251
AEETSFVFSKFKPLEPNLILQGDALVTVAGVLQLTNVDKNGVPEPSSLGRATYSAPINIWDSATGLVASFATSFRFTIYAPNIATIADGLAFFLAPVASAPDSGGGFLGLFDSAVSGSTYQTVAVEFDTYENTVFTDPPYTHIGFDVNSISSIKTVKWSLANGEAAKVLITYNSAVKLLVASLVYPSSKTSFILADIVDLSSVLPEWVRVGFSAATGASGGKIETHDVFSWSFASKLAGXXTKDSSFLDGG

Formula C1199H1831N289O366

Absent Amino Acids CM

Common Amino Acids S

Mass 26150.44

PI 4.38

Basic Residues 16

Acidic Residues 23

Hydrophobic Residues 115

Net Charge -9

Boman Index 14.77

Hydrophobicity 0.301

Aliphatic Index 92.11

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 32430

Absorbance 280nm 124.01

Polar Residues 70

number

28

A

3

R

9

N

14

D

0

C

9

E

3

Q

20

G

2

H

13

I

22

L

11

K

0

M

18

F

12

P

31

S

20

T

4

W

7

Y

23

V

Amino Acid Distribution

A: 28 R: 3 N: 9 D: 14 C: 0 E: 9 Q: 3 G: 20 H: 2 I: 13 L: 22 K: 11 M: 0 F: 18 P: 12 S: 31 T: 20 W: 4 Y: 7 V: 23

Length

251

Formula

C1199H1831N289O366

Mass

26150.44

PI

4.38

Net Charge

-9

Boman Index

14.77

Hydrophobicity

0.301

Evidence 1 Activity

Source & Reference

Database Source CAFPdb