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Peptide record

TPDB17856

Antibacterial Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB17856
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 31-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
ADPRVKKVLGVAMQIRKAQLMREKLNSIMRR
Physicochemical Analysis
C156H283N53O40S3
CHFTWY
R
3637.47
12.25
9
2
14
+7
10.14
-0.461
100.65
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
3
A
5
R
1
N
1
D
0
C
1
E
2
Q
1
G
0
H
2
I
3
L
4
K
3
M
0
F
1
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 5 N: 1 D: 1 C: 0 E: 1 Q: 2 G: 1 H: 0 I: 2 L: 3 K: 4 M: 3 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
31
C156H283N53O40S3
3637.47
12.25
+7
10.14
-0.461
Evidence Records 1 records
Evidence 1 Activity

Activity

<7% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
<7% Hemolysis | 500 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
LcCCL28-25, Derived from Piscine Chemokine, Exhibits Antimicrobial Activity against Gram-Negative and Gram-Positive Bacteria In Vitro and In Vivo | Microbiol Spectr | 2022