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Peptide record

TPDB17805

Antibacterial Anticancer Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB17805
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AAVALLPAVLLALLAPMPFSTGKRIMLGE
Physicochemical Analysis
C138H235N33O34S2
NDCQHWY
L
2964.70
10.09
2
1
19
+1
-1.24
1.307
148.28
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
6
A
1
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
1
I
7
L
1
K
2
M
1
F
3
P
1
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 6 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 1 L: 7 K: 1 M: 2 F: 1 P: 3 S: 1 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
29
C138H235N33O34S2
2964.70
10.09
+1
-1.24
1.307
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Use of a novel cytotoxic HEXIM1 peptide in the directed breast cancer therapy. | Oncotarget | 2016
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human foreskin fibroblasts (HFF)

Target

Human foreskin fibroblasts (HFF)

Source & Reference

NA
DBAASP
Use of a novel cytotoxic HEXIM1 peptide in the directed breast cancer therapy. | Oncotarget | 2016
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: HEK293: Not active up to 100 µM HFF: Not active up to 100 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Oncotarget. 2016 Feb 2 7(5):5483-94.