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Peptide record

TPDB17776

Antibacterial Antiviral Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB17776
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
AACEVAKNLNESLIDLQELGKYEQYIKW
Physicochemical Analysis
C147H230N36O46S1
RHMFPT
EL
3269.72
4.36
3
5
13
-2
7.15
-0.414
104.64
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
8480
259.35
8
Residue Composition
number
3
A
0
R
2
N
1
D
1
C
4
E
2
Q
1
G
0
H
2
I
4
L
3
K
0
M
0
F
0
P
1
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 1 C: 1 E: 4 Q: 2 G: 1 H: 0 I: 2 L: 4 K: 3 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
28
C147H230N36O46S1
3269.72
4.36
-2
7.15
-0.414
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Cytotoxicity
Toxicity
30 µM
Cytotoxic
0% Cytotoxicity | 30 | µM | target cell: Vero E6 cells

Target

Vero E6 cells

Source & Reference

NA
DBAASP
Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein. | Virus Res | 2006
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.16616792]No cytotoxic at a concentration of 30 µM on Vero-E6 cells

Source & Reference

NA
DRAMP
Virus Res. 2006 Sep 120(1-2):146-55.
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.16616792]No cytotoxicity against Vero E6 cells up to 30 µM.

Source & Reference

NA
DRAMP
Virus Res. 2006 Sep 120(1-2):146-55.