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Peptide record

TPDB17555

Antibacterial Anticancer Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB17555
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
DRAMP Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from DRAMP and Peptipedia, with an available 3D structural model.
Sequence
SKVWRHWRRFWHRAHRKL
Physicochemical Analysis
C119H176N44O20
NDCEQGIMPTY
R
2542.99
13.01
10
0
7
+7
1.70
-1.711
43.33
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
16500
648.84
1
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
3
H
0
I
1
L
2
K
0
M
1
F
0
P
1
S
0
T
3
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 3 I: 0 L: 1 K: 2 M: 0 F: 1 P: 0 S: 1 T: 0 W: 3 Y: 0 V: 1
Chemical Descriptors
18
C119H176N44O20
2542.99
13.01
+7
1.70
-1.711
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>500 µM
Hemolytic Cytotoxic
50% Hemolysis | >500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity and Self-Assembly Behavior of Antimicrobial Peptide chensinin-1b With Lipophilic Alkyl Tails | Eur J Med Chem | 2018
Evidence 2 Activity

Activity

HC50
Toxicity
500 µM
Hemolytic
Hemolytic_activity: [Ref.29549839] HC50>500 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur J Med Chem. 2018 Apr 25 150:546-558.