TPDB

3D PDB MODEL

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TPDB ID TPDB17551

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 270-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

QKLPVPIPPPTNPPVAAFHNSVATNSKGGQDVSVKLAATNLGNKHVQPIAEVFAEGNTKGGNVIRGATVGVQGHGLGASVTKSGNGIAESFRKQAEANLRLGDSASLIGKVSQTDTKIKGIDFKPQLSSSSLALQGDRLGASISRDVNRGVSDTLTKSISANVFRNDNHNLDASVFRSDVRQNNGFNFQKTGGMLDYSHANGHGLNAGLTRFSGIGNQANVGGYSTLFRSNDGLTSLKANAGGSQWLSGPFANQRDYSFGLGLSHNAWRG

FASTA

>TPDB17551|Antibacterial|length=270
QKLPVPIPPPTNPPVAAFHNSVATNSKGGQDVSVKLAATNLGNKHVQPIAEVFAEGNTKGGNVIRGATVGVQGHGLGASVTKSGNGIAESFRKQAEANLRLGDSASLIGKVSQTDTKIKGIDFKPQLSSSSLALQGDRLGASISRDVNRGVSDTLTKSISANVFRNDNHNLDASVFRSDVRQNNGFNFQKTGGMLDYSHANGHGLNAGLTRFSGIGNQANVGGYSTLFRSNDGLTSLKANAGGSQWLSGPFANQRDYSFGLGLSHNAWRG

Formula C1222H1941N377O389S1

Absent Amino Acids C

Common Amino Acids G

Mass 28170.21

PI 10.48

Basic Residues 34

Acidic Residues 17

Hydrophobic Residues 92

Net Charge +11

Boman Index 45.26

Hydrophobicity -0.423

Aliphatic Index 74.44

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 15470

Absorbance 280nm 54.92

Polar Residues 84

number

24

A

13

R

25

N

13

D

0

C

4

E

13

Q

36

G

7

H

10

I

22

L

14

K

1

M

12

F

10

P

29

S

14

T

2

W

3

Y

18

V

Amino Acid Distribution

A: 24 R: 13 N: 25 D: 13 C: 0 E: 4 Q: 13 G: 36 H: 7 I: 10 L: 22 K: 14 M: 1 F: 12 P: 10 S: 29 T: 14 W: 2 Y: 3 V: 18

Length

270

Formula

C1222H1941N377O389S1

Mass

28170.21

PI

10.48

Net Charge

+11

Boman Index

45.26

Hydrophobicity

-0.423

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.