TPDB

3D PDB MODEL

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TPDB ID TPDB17543

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 265-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEERKIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWVSFLKEEAGHYPLEKRVEECLRGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLKF

FASTA

>TPDB17543|Antibacterial|length=265
MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEERKIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWVSFLKEEAGHYPLEKRVEECLRGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVVNPEALILLKF

Formula C1379H2170N358O409S4

Absent Amino Acids

Common Amino Acids E

Mass 30436.79

PI 4.70

Basic Residues 39

Acidic Residues 50

Hydrophobic Residues 107

Net Charge -13

Boman Index 81.77

Hydrophobicity -0.301

Aliphatic Index 97.06

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 36565

Absorbance 280nm 120.13

Polar Residues 46

number

12

A

18

R

6

N

15

D

3

C

35

E

5

Q

19

G

2

H

16

I

32

L

19

K

1

M

15

F

10

P

13

S

13

T

5

W

6

Y

20

V

Amino Acid Distribution

A: 12 R: 18 N: 6 D: 15 C: 3 E: 35 Q: 5 G: 19 H: 2 I: 16 L: 32 K: 19 M: 1 F: 15 P: 10 S: 13 T: 13 W: 5 Y: 6 V: 20

Length

265

Formula

C1379H2170N358O409S4

Mass

30436.79

PI

4.70

Net Charge

-13

Boman Index

81.77

Hydrophobicity

-0.301

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.