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Peptide record

TPDB17309

Antibacterial Antifungal Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB17309
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia CAFPdb
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, and CAFPdb, with an available 3D structural model.
Sequence
IKCVPSQCNQICRVLGKKCGYCKNASTCVCL
Physicochemical Analysis
C139H240N42O40S7
DEHMFW
C
3364.11
8.67
5
0
9
+5
3.32
0.271
81.61
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1865
55.44
15
Residue Composition
number
1
A
1
R
2
N
0
D
7
C
0
E
2
Q
2
G
0
H
2
I
2
L
4
K
0
M
0
F
1
P
2
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 0 C: 7 E: 0 Q: 2 G: 2 H: 0 I: 2 L: 2 K: 4 M: 0 F: 0 P: 1 S: 2 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
31
C139H240N42O40S7
3364.11
8.67
+5
3.32
0.271
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Toxicity
9.73 µM
Cytotoxic
IC50 | 9.73 | µM | target cell: Human fibroblasts MRC-5 SV2

Target

Human fibroblasts MRC-5 SV2

Source & Reference

NA
DBAASP
In Vitro Evaluation of Antimicrobial Peptides from the Black Soldier Fly (Hermetia Illucens) against a Selection of Human Pathogens. | Microbiol Spectr | 2022